SCHEMBL8843889

SCHEMBL8843889

CCCC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.69
XDH P47989 3/20 0.61
POLA1 P09884 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5352883 0.90 XDH (0.67) GDAXDHPOLA1
SCHEMBL1965519 0.88 GDA (0.71) GDAXDHPOLA1
SCHEMBL3072990 0.83 GDA (0.67) GDAXDH
SCHEMBL27569987 0.82 GDA (0.59) GDAXDHPOLA1
SCHEMBL27550540 0.82 GDA (0.59) GDAXDHPOLA1
SCHEMBL219478 0.82 GDA (1.00) GDAXDHPOLA1
SCHEMBL25398222 0.82 GDA (0.58) GDAPOLA1
SCHEMBL19466100 0.81 GDA (0.76) GDAXDHPOLA1
SCHEMBL29411658 0.80 GDA (0.76) GDAXDHPOLA1
SCHEMBL31093422 0.80 GDA (0.74) GDAXDHPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023054391-A1 NUCLEIC ACID STRAND CLEAVING METHOD, NUCLEIC ACID STRAND CLEAVING DEVICE, DOUBLE-STRANDED DNA PRODUCTION METHOD, AND DOUBLE-STRANDED DNA PRODUCTION DEVICE 国立研究開発法人科学技術振興機構 2023-04-06 WO disclosed
WO-1997032589-A1 COMBINATIONS FOR TREATMENT OF PROLIFERATIVE DISEASES NOVARTIS AG (CH) 1997-09-12 WO disclosed
WO-1997032604-A1 ANTIPROLIFERATIVE COMBINATIONS, CONTAINING RAF-TARGETED OLIGONUCLEOTIDES AND CHEMOTHERAPEUTIC COMPOUNDS NOVARTIS AG (CH) 1997-09-12 WO disclosed