SCHEMBL3072990

SCHEMBL3072990

COCC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.67
XDH P47989 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31093422 0.84 GDA (0.74) GDAXDH
SCHEMBL8843889 0.83 GDA (0.69) GDAXDH
SCHEMBL1970070 0.83 GDA (0.58) GDA
SCHEMBL1965519 0.82 GDA (0.71) GDAXDH
SCHEMBL219478 0.81 GDA (1.00) GDAXDH
SCHEMBL19466100 0.80 GDA (0.76) GDAXDH
SCHEMBL29411658 0.79 GDA (0.76) GDAXDH
SCHEMBL5352883 0.79 XDH (0.67) GDAXDH
SCHEMBL2343363 0.79 XDH (0.65) GDAXDH
SCHEMBL30510976 0.78 GDA (0.74) GDAXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790843-B2 Cypin polypeptide and fragments thereof RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2010-09-07 US disclosed
US-20080182970-A1 Using cypin in assays, diagnostics and treatment of cognitive disorders RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2008-07-31 US disclosed
US-7338769-B2 Methods for identifying agonists of cypin RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2008-03-04 US disclosed
US-20050214822-A1 Using cypin in assays, diagnostics and treatment of cognitive disorders RUTGERS, THE STATE UNIVERSITY OF NEV 2005-09-29 US disclosed