Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227230 | 0.81 | MAPK1 (0.58) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL8791392 | 0.78 | JAK2 (0.46) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL9092590 | 0.78 | JAK2 (0.46) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL9091439 | 0.78 | JAK2 (0.46) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL8409834 | 0.78 | JAK2 (0.46) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL8406702 | 0.78 | JAK2 (0.46) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL8409521 | 0.77 | DRD2 (0.61) | MAPK1SIGMAR1ACHEKMT2AMEN1 | |
| SCHEMBL6166008 | 0.77 | MAPK1 (0.69) | MAPK1SIGMAR1ACHEBCHEBACE1 | |
| SCHEMBL8844679 | 0.77 | CYP3A4 (0.46) | ACHEBCHEBACE1CYP2D6USP30 | |
| SCHEMBL8844616 | 0.76 | ACHE (0.48) | ACHEBCHEBACE1CYP2D6USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622966-A | BACTERICIDES TREATING INFECTIONS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5446044-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5384407-A | Pyrrolidine compounds | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| US-5342844-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| WO-1993016077-A1 | 7-SUBSTITUTED QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |
| US-5221676-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1993-06-22 | — | — | US | disclosed |