Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905545 | 0.88 | HTR1A (0.32) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8845003 | 0.85 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL8844088 | 0.82 | HTR1A (0.32) | HTR1ADRD2 | |
| SCHEMBL8844167 | 0.82 | HTR1A (0.32) | HTR1ADRD2 | |
| SCHEMBL9274799 | 0.81 | HTR1A (0.33) | HTR1ADRD2 | |
| Tivirapine SCHEMBL377308 | 0.81 | HTR1A (0.31) | HTR1ADRD2 | |
| Tivirapine SCHEMBL3145162 | 0.81 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL17938151 | 0.80 | PSMB8 (0.32) | HTR1ADRD2 | |
| Tivirapine SCHEMBL8844208 | 0.80 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL8844204 | 0.80 | PSMB8 (0.33) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599982-A | Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-02-04 | — | — | US | disclosed |
| US-5543570-A | Intermediates for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2-(1H)-thiones | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-06 | — | — | US | disclosed |
| US-5463049-A | Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-31 | — | — | US | disclosed |