Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843864 | 0.89 | ALOX5 (0.50) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL25306709 | 0.79 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8988345 | 0.76 | MAPT (0.67) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL22162812 | 0.74 | CA12 (0.58) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3901839 | 0.72 | CA12 (0.61) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL13376227 | 0.72 | GAA (0.67) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL26923012 | 0.71 | KDM4E (0.50) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29629010 | 0.71 | PTGS2 (0.58) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL2692579 | 0.71 | CA12 (0.59) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3492339 | 0.71 | NPC1 (0.81) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |