Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.56 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569983 | 0.93 | TRPV6 (0.64) | TP53MDM2TRPV6CCR5SIGMAR1 | |
| SCHEMBL6023725 | 0.85 | MEN1 (0.68) | TP53CCR5SIGMAR1MEN1KMT2A | |
| SCHEMBL22755777 | 0.85 | MEN1 (0.68) | TP53CCR5SIGMAR1MEN1KMT2A | |
| SCHEMBL3598146 | 0.85 | MEN1 (0.68) | TP53CCR5SIGMAR1MEN1KMT2A | |
| SCHEMBL6956567 | 0.84 | TP53 (0.54) | TP53MDM2TRPV6CCR5SIGMAR1 | |
| SCHEMBL31328408 | 0.84 | DRD4 (0.48) | TP53MDM2TRPV6CCR5MEN1 | |
| SCHEMBL29832299 | 0.84 | TRPV6 (0.64) | TRPV6CCR5SIGMAR1MEN1KMT2A | |
| SCHEMBL8844231 | 0.84 | TRPV6 (0.57) | TRPV6CCR5SIGMAR1MEN1KMT2A | |
| SCHEMBL15732590 | 0.81 | MGLL (0.46) | TP53MDM2TRPV6CCR5PDCD1LG2 | |
| SCHEMBL25272839 | 0.81 | CNR2 (0.60) | TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622966-A | BACTERICIDES TREATING INFECTIONS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5446044-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5384407-A | Pyrrolidine compounds | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| US-5342844-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| WO-1993016077-A1 | 7-SUBSTITUTED QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |
| US-5221676-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1993-06-22 | — | — | US | disclosed |