SCHEMBL884501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL885985	0.93	ROCK2 (0.37)	PTGIRKMT2AALDH1A1USP2CYP1A2
	SCHEMBL884353	0.90	CCR8 (0.38)	PTGIRKMT2AALDH1A1USP2CYP1A2
	SCHEMBL885006	0.90	ALDH1A1 (0.37)	PTGIRKMT2AALDH1A1USP2CYP1A2
	SCHEMBL885883	0.89	ALDH1A1 (0.38)	PTGIRKMT2AALDH1A1USP2CYP2D6
	SCHEMBL2062699	0.89	KMT2A (0.45)	KMT2AALDH1A1USP2CYP1A2CYP3A4
	SCHEMBL884945	0.89	KMT2A (0.45)	KMT2AALDH1A1USP2CYP1A2CYP3A4
	SCHEMBL884507	0.88	REN (0.39)	PTGIRKMT2AALDH1A1USP2CYP1A2
	SCHEMBL884466	0.88	KDM4E (0.42)	KMT2AALDH1A1MAPTLMNACHRM3
	SCHEMBL2062327	0.88	KDM4E (0.42)	KMT2AALDH1A1MAPTLMNACHRM3
	SCHEMBL2062692	0.88	KDM4E (0.42)	KMT2AALDH1A1MAPTLMNACHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.