Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845328 | 0.91 | CYP19A1 (0.44) | KCNJ1KCNH2MAPTSMN1; SMN2HTT | |
| SCHEMBL8845438 | 0.88 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2SLC29A1KMT2ARAB9A | |
| SCHEMBL8845309 | 0.86 | MAPT (0.46) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL8845468 | 0.85 | CYP19A1 (0.40) | KCNJ1MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8845405 | 0.85 | SLC29A1 (0.40) | KCNJ1KCNH2MAPTSMN1; SMN2HTT | |
| SCHEMBL8845463 | 0.85 | KCNJ1 (0.44) | KCNJ1KCNH2MAPTSMN1; SMN2HTT | |
| SCHEMBL8845932 | 0.85 | BCHE (0.45) | MAPTSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL8845414 | 0.83 | KCNJ1 (0.47) | KCNJ1KCNH2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8845454 | 0.83 | TGM2 (0.46) | KCNJ1MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8845195 | 0.76 | POLB (0.37) | KCNJ1MAPTSMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674886-A | AROMATASE INHIBITOR; BREAST CANCER; UROGENITAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-07 | — | — | US | disclosed |