Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845328 | 0.95 | CYP19A1 (0.44) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845438 | 0.89 | SMN1; SMN2 (0.44) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8845463 | 0.89 | KCNJ1 (0.44) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845468 | 0.89 | CYP19A1 (0.40) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845405 | 0.89 | SLC29A1 (0.40) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845932 | 0.89 | BCHE (0.45) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845246 | 0.86 | KCNJ1 (0.47) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845454 | 0.86 | TGM2 (0.46) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8845414 | 0.86 | KCNJ1 (0.47) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8845195 | 0.82 | POLB (0.37) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674886-A | AROMATASE INHIBITOR; BREAST CANCER; UROGENITAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-07 | — | — | US | disclosed |