Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845540 | 0.78 | SLC6A2 (0.49) | ITGB3ITGAV | |
| SCHEMBL9152666 | 0.78 | FAAH (0.43) | FAAHEPHX1ACHEMAPK1 | |
| SCHEMBL8845539 | 0.77 | SLC6A2 (0.56) | ITGB3ITGAVACHE | |
| SCHEMBL9738763 | 0.77 | SLC6A2 (0.61) | FAAHEPHX1ACHE | |
| Hydrochloric Acid SCHEMBL8544479 | 0.76 | SLC6A2 (0.60) | FAAHEPHX1ACHE | |
| SCHEMBL8845735 | 0.75 | SLC6A2 (0.49) | ITGB3ITGAV | |
| SCHEMBL8845533 | 0.75 | FAAH (0.49) | FAAHEPHX1ACHE | |
| SCHEMBL9196729 | 0.74 | SLC6A2 (0.52) | ITGB3ITGAVACHE | |
| SCHEMBL8845725 | 0.72 | SLC6A2 (0.54) | FAAHEPHX1ITGB3ITGAVACHE | |
| SCHEMBL8845670 | 0.72 | ITGB3 (0.40) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0471298-B1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| US-5455245-A | Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5264442-A | For treating alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0471298-A1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |