Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.42 |
| ▸ | ITGAV | P06756 | 10/20 | 0.42 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196729 | 0.86 | SLC6A2 (0.52) | SLC6A2ITGB3ITGAVKMT2AITGB5 | |
| SCHEMBL8845539 | 0.86 | SLC6A2 (0.56) | SLC6A2ITGB3ITGAVITGB5 | |
| SCHEMBL8845665 | 0.83 | LIPE (0.43) | SLC6A2ITGB3ITGAVLIPEITGB5 | |
| SCHEMBL8845725 | 0.80 | SLC6A2 (0.54) | SLC6A2ITGB3ITGAVITGB5 | |
| SCHEMBL9155328 | 0.80 | SLC6A2 (0.56) | SLC6A2ITGB3ITGAVKMT2AITGB5 | |
| SCHEMBL8845735 | 0.78 | SLC6A2 (0.49) | SLC6A2ITGB3ITGAVITGB5 | |
| SCHEMBL8845528 | 0.78 | FAAH (0.48) | ITGB3ITGAV | |
| SCHEMBL9197969 | 0.77 | SLC6A2 (0.65) | SLC6A2ITGB3ITGAV | |
| SCHEMBL9672902 | 0.77 | SLC6A2 (0.62) | SLC6A2LIPE | |
| SCHEMBL8845716 | 0.76 | SLC6A2 (0.55) | SLC6A2ITGB3ITGAVLIPEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| US-5455245-A | Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5264442-A | For treating alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0471298-A1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |