Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080028 | 0.79 | MEN1 (0.46) | MEN1KMT2AMAOBMAOAL3MBTL1 | |
| SCHEMBL11878297 | 0.78 | LTA4H (0.50) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28357743 | 0.75 | DPP4 (0.42) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22069540 | 0.74 | MEN1 (0.40) | MEN1KMT2AMAOBMAOASMN1; SMN2 | |
| SCHEMBL1641588 | 0.74 | RAB9A (0.45) | MEN1KMT2AMAOBMAOASMN1; SMN2 | |
| SCHEMBL8845612 | 0.74 | ESR2 (0.44) | MEN1KMT2A | |
| SCHEMBL13562892 | 0.72 | MAOB (0.48) | MEN1KMT2AMAOBMAOAOPRM1 | |
| SCHEMBL5076533 | 0.72 | MEN1 (0.39) | MEN1KMT2AMAOBMAOAOPRM1 | |
| SCHEMBL9115407 | 0.70 | OPRM1 (0.40) | MEN1KMT2AMAOBMAOASMN1; SMN2 | |
| SCHEMBL23888569 | 0.69 | MEN1 (0.41) | MEN1KMT2AMAOBMAOASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658914-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658951-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658927-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5422367-A | A hormon inhibitors and for inhibiting the development of an estrogen-dependent tumor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-06-06 | — | — | US | disclosed |
| US-5098903-A | Halocyclopropanes | BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 1992-03-24 | — | — | US | disclosed |
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |
| US-3962356-A | INSECTICIDES | MONSANTO CHEMICALS LIMITED (AU) | 1976-06-08 | — | — | US | disclosed |