Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693231 | 0.81 | HTR6 (0.46) | PLGPLAU | |
| SCHEMBL8845775 | 0.76 | PLG (0.45) | CDK4CCND1HRH1PLGPLAU | |
| SCHEMBL16720003 | 0.76 | CDK4 (0.44) | CDK4CCND1 | |
| SCHEMBL16719844 | 0.75 | CDK4 (0.44) | CDK4CCND1PLGPLAU | |
| SCHEMBL5814894 | 0.75 | CDK4 (0.44) | CDK4CCND1PLGPLAU | |
| SCHEMBL9502777 | 0.74 | SLC6A2 (0.48) | HRH1SIGMAR1CYP24A1 | |
| SCHEMBL6754186 | 0.71 | HTR2A (0.50) | CDK4CCND1 | |
| SCHEMBL5778093 | 0.71 | GLO1 (0.41) | CDK4CCND1PLGPLAU | |
| SCHEMBL694594 | 0.71 | CDK4 (0.41) | CDK4CCND1 | |
| SCHEMBL1450476 | 0.71 | CDK4 (0.41) | CDK4CCND1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |