Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846005 | 0.92 | RXRA (0.44) | PPARGFFAR1RXRARXRBRXRG | |
| SCHEMBL8846043 | 0.88 | FFAR1 (0.48) | PPARGFFAR1RXRARXRBRXRG | |
| SCHEMBL8846083 | 0.84 | MRGPRX4 (0.42) | PPARGRXRARXRBRXRGRARA | |
| SCHEMBL8846206 | 0.82 | RARG (0.47) | PPARGRXRARXRBRXRGRARA | |
| SCHEMBL8846492 | 0.81 | RARB (0.49) | PPARGFFAR1RXRARXRBRXRG | |
| SCHEMBL8845951 | 0.80 | RXRA (0.47) | PPARGRXRARXRBRXRGRARA | |
| SCHEMBL8846554 | 0.80 | RXRA (0.46) | PPARGRXRARXRBRXRGRARA | |
| SCHEMBL8846008 | 0.80 | RXRA (0.46) | PPARGFFAR1RXRARXRBRXRG | |
| SCHEMBL8846089 | 0.79 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8846139 | 0.79 | S1PR1 (0.45) | FFAR1RARARARBRARGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | claimed |