Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARG | P13631 | 4/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846492 | 0.89 | RARB (0.49) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8845921 | 0.87 | PTGER1 (0.54) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846043 | 0.86 | FFAR1 (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846008 | 0.86 | RXRA (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846005 | 0.85 | RXRA (0.44) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846206 | 0.84 | RARG (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846090 | 0.83 | RARB (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846040 | 0.81 | PTGER1 (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8845892 | 0.81 | PTGER1 (0.56) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846145 | 0.80 | PPARG (0.41) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | claimed |