Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846145 | 0.92 | PPARG (0.41) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846083 | 0.90 | MRGPRX4 (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8845951 | 0.88 | RXRA (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846554 | 0.85 | RXRA (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846008 | 0.85 | RXRA (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846127 | 0.85 | CFD (0.53) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846043 | 0.83 | FFAR1 (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8845862 | 0.83 | KMT2A (0.44) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846492 | 0.82 | RARB (0.49) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8846206 | 0.82 | RARG (0.47) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | claimed |