SCHEMBL8846567

SCHEMBL8846567

Nc1cccc(C(=O)OCCO)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.57
ADRB2 P07550 2/20 0.51
ADRB1 P08588 2/20 0.51
ADRB3 P13945 2/20 0.51
CHRNB2 P17787 1/20 0.49
CHRNA4 P43681 1/20 0.49
PBRM1 Q86U86 1/20 0.49
TDP1 Q9NUW8 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
ELANE P08246 1/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 1/20 0.44
LMNA P02545 4/20 0.43
ALDH1A1 P00352 1/20 0.43
SERPINE1 P05121 1/20 0.43
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1802562 0.91 ADRB2 (0.55) SLC7A5ADRB2ADRB1ADRB3CHRNB2
SCHEMBL8846590 0.90 TDP1 (0.51) SLC7A5ADRB2ADRB1ADRB3CHRNB2
SCHEMBL1795012 0.88 TDP1 (0.56) SLC7A5ADRB2ADRB1ADRB3CHRNB2
SCHEMBL1804032 0.88 TDP1 (0.61) SLC7A5ADRB2ADRB1ADRB3CHRNB2
SCHEMBL134602 0.87 SLC7A5 (0.60) SLC7A5TDP1CA1CA2CYP4F2
SCHEMBL19032982 0.86 ADRB2 (0.51) SLC7A5ADRB2ADRB1ADRB3CHRNB2
SCHEMBL5310805 0.86 TDP1 (0.59) ADRB2ADRB1ADRB3CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL9751464 0.86 TDP1 (0.59) ADRB2ADRB1ADRB3CHRNB2CHRNA4
Cyclopropane SCHEMBL3688810 0.86 CHRNB2 (0.56) SLC7A5ADRB2ADRB1ADRB3CHRNB2
SCHEMBL1928911 0.86 TDP1 (0.59) ADRB2ADRB1ADRB3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0437821-B1 Method for producing polyimide foam products. IMI TECH CORP (US) 1997-07-30 EP disclosed
US-5453161-A Polyamic acid to polyimide conversion by microwave heating ENICHEM S.P.A. (IT) 1995-09-26 US disclosed
EP-0351544-B1 Production of foamed polymer structures ALBEMARLE CORP (US) 1994-10-05 EP disclosed
EP-0349796-B1 Production of foamed polymer structures ETHYL CORP (US) 1994-09-21 EP disclosed
EP-0348722-B1 Production of foamed polymer structures ETHYL CORP (US) 1994-08-17 EP disclosed
US-5234966-A Adding to precursor polar protic foam-enhancing additive ETHYL CORPORATION (US) 1993-08-10 US disclosed
US-5122546-A Slurry of equimolar amounts of lower alkyl diester of tetracarboxylic acid, diamine, and volatile polar protic foam enhancing additive ETHYL CORPORATION (US) 1992-06-16 US disclosed
US-5096932-A Adding polar, protic foaming agent to aromatic diamine and tetracarboxylic acid ester; slurrying, curing ETHYL CORPORATION (US) 1992-03-17 US disclosed
US-5077318-A Adding a foam-enhancing polar protic alcohol or water to the polyimide melt ETHYL CORPORATION (US) 1991-12-31 US disclosed
US-5064867-A Microwaves, Compression ETHYL CORPORATION (US) 1991-11-12 US disclosed
US-4874452-A SUBJECTING CURED POLYIMIDE FOAM TO PRESSURIZED STEAM IMI-TECH CORPORATION (US) 1989-10-17 US disclosed
US-4866104-A FLEXIBILITY, SOFTNESS ETHYL CORPORATION (US) 1989-09-12 US disclosed
US-4855331-A FOAMING BY MICROWAVE RADIATION UNDER A VAPOR IMPERMIABLE SHIEL D ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4855332-A 2-/VICINAL-DICARBOXYCYCLOHEXENYUL/SUCCINIC ACID ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4839398-A FLEXIBILITY, COMPRESSIVE STRENGTH, AGING RESISTANCE ETHYL CORPORATION (US) 1989-06-13 US disclosed
US-4826886-A AIRCRAFT SEAT CUSHIONS ETHYL CORPORATION (US) 1989-05-02 US disclosed
US-4822537-A MICROWAVE IRRADIATION OF POLYIMIDE ETHYL CORPORATION (US) 1989-04-18 US disclosed
US-4816493-A TETRACARBOXYLIC ACID, AMINOAROMATIC ACID, ESTER OF DIOL ETHYL CORPORATION (US) 1989-03-28 US disclosed
US-4814357-A Polyimide foams and their preparation ETHYL CORPORATION (US) 1989-03-21 US disclosed
US-4804504-A MICROWAVE RADIATION OF POLYIMIDE PRECURSOR UNDER VAPOR IMPERMEABLE COVERING ETHYL CORPORATION (US) 1989-02-14 US disclosed