Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804032 | 0.96 | TDP1 (0.61) | TDP1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL1928911 | 0.95 | TDP1 (0.59) | TDP1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL5310805 | 0.95 | TDP1 (0.59) | TDP1ADRB2ADRB1ADRB3LMNA | |
| Hydrochloric Acid SCHEMBL9751464 | 0.95 | TDP1 (0.59) | TDP1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL1802562 | 0.93 | ADRB2 (0.55) | TDP1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL8846590 | 0.92 | TDP1 (0.51) | TDP1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL5175629 | 0.90 | CYP1A2 (0.67) | TDP1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8780011 | 0.89 | TDP1 (0.53) | TDP1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL28280195 | 0.89 | ALDH1A1 (0.66) | TDP1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8846567 | 0.88 | SLC7A5 (0.57) | TDP1ADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280976-A1 | TWO-COMPONENT ADHESIVE | NOLAX AG (CH) | 2016-09-29 | — | — | US | disclosed |
| US-7951870-B2 | Golf ball compositions having in-situ or reactive impact modified silicone-urea or silicone urethane | ACUSHNET COMPANY (US) | 2011-05-31 | — | — | US | disclosed |
| US-7825208-B2 | Golf equipment formed from amine-adduct modified polyurea compositions | ACUSHNET COMPANY (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100108260-A1 | Two-Component Adhesive | NOLAX AG (CH) | 2010-05-06 | — | — | US | disclosed |
| US-7705102-B2 | Coverings for golf balls of a polysiloxaneurea copolymer based on a polysiloxane having an oxirane-terminated end group reacted with adiamine followed by a diisocyanate; controllable kinetics; homogeneity;shrinkage inhibition; chemical resistance; thermoplastic resins | ACUSHNET COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-20070117656-A1 | Golf ball compositions having in-situ or reactive impact modified silicone-urea or silicone urethane | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2007-05-24 | — | — | US | disclosed |
| US-20060178233-A1 | Golf equipment formed from amine-adduct modified polyurea compositions | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-08-10 | — | — | US | disclosed |
| US-20060173139-A1 | Golf equipment formed from amine-adduct modified polyurea compositions | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-08-03 | — | — | US | disclosed |
| US-20030212291-A1 | Diamine curing agents for the preparation of polyurethane-urea elastomers | CROMPTON CORPORATION | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212291-A1 | Diamine curing agents for the preparation of polyurethane-urea elastomers | AOC1, DDC, UROD | TDP1 1077/4885ADRB2 2174/4885ADRB1 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.