SCHEMBL8846593

SCHEMBL8846593

O=C(O)C=CC(O)=CCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TP53 P04637 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50
EGLN3 Q9H6Z9 1/20 0.50
GABRR1 P24046 2/20 0.36
GABRR2 P28476 2/20 0.36
BLM P54132 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
GABRR3 A8MPY1 1/20 0.36
LMNA P02545 1/20 0.36
APEX1 P27695 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HCAR2 Q8TDS4 6/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 2/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
RECQL P46063 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL3435263 0.74
Maleic Acid SCHEMBL2525505 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Maleic Acid SCHEMBL28461661 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Maleic Acid SCHEMBL27945335 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Fumaric Acid SCHEMBL27990610 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Fumaric Acid SCHEMBL10780619 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Maleic Acid SCHEMBL215107 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Fumaric Acid SCHEMBL303957 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Fumaric Acid SCHEMBL22117153 0.72 TSHR (0.69) TSHRTP53EGLN1EGLN3GABRR1
Fumaric Acid SCHEMBL4142780 0.71 TSHR (0.82) TSHRTP53EGLN1EGLN3GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421184-B1 Process for producing vinyl chloride resin KANEGAFUCHI CHEMICAL IND (JP) 1997-04-09 EP disclosed
EP-0688797-A2 Polymerization apparatus and process for the microsuspension or emulsion polymerization of vinyl chloride KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-12-27 EP disclosed
US-5278262-A Process control KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-01-11 US disclosed
US-5169918-A Agitator improvement in microsuspension polymerization of vinyl chloride KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-12-08 US disclosed
EP-0421184-A2 Polymerization reactor for producing vinyl chloride resin KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-04-10 EP disclosed