Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.54 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.43 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.43 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647789 | 0.90 | GCGR (0.55) | GCGRSLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2648212 | 0.88 | GCGR (0.62) | GCGRSLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2649262 | 0.85 | GCGR (0.50) | GCGRSLC10A2ALDH1A1 | |
| SCHEMBL2649264 | 0.85 | GCGR (0.50) | GCGRSLC10A2ALDH1A1 | |
| SCHEMBL5102017 | 0.83 | GCGR (0.49) | GCGRSLC10A2ALDH1A1L3MBTL1CACNB4 | |
| SCHEMBL2648227 | 0.82 | GCGR (0.60) | GCGRSLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2647286 | 0.82 | GCGR (0.79) | GCGR | |
| SCHEMBL2647128 | 0.82 | GCGR (0.51) | GCGRSLC10A2ALDH1A1L3MBTL1CACNB4 | |
| SCHEMBL9268564 | 0.81 | GCGR (0.64) | GCGRALDH1A1L3MBTL1 | |
| SCHEMBL2649395 | 0.80 | GCGR (0.47) | GCGRSLC10A2ALDH1A1L3MBTL1CACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641762-B1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES (JP) | 1997-05-28 | — | — | EP | disclosed |
| US-5457225-A | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0641762-A1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |