SCHEMBL8846804

SCHEMBL8846804

C=COC(=O)CCC(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MAPK1 P28482 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
HCAR2 Q8TDS4 1/20 0.47
TDP1 Q9NUW8 3/20 0.47
KMT2A Q03164 2/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
NOTUM Q6P988 1/20 0.47
LMNA P02545 3/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
TGM2 P21980 1/20 0.43
PKM P14618 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CDC25B P30305 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11064051 0.87 PKM (0.57) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL1177836 0.86 ALDH1A1 (0.73) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL24246693 0.82 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL2465566 0.81 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL5793033 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL21861568 0.81 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL7632247 0.81 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL347597 0.81 TDP1 (0.61) ALDH1A1MAPK1TDP1KMT2ASLC6A3
SCHEMBL1865174 0.81 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL11061194 0.81 PKM (0.55) ALDH1A1MAPK1L3MBTL1HCAR2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633327-A Styrene-based dicarboxylic acid-functional monomers and polymers prepared from same THE SHERWIN-WILLIAMS COMPANY (US) 1997-05-27 US disclosed
US-5510440-A Styrene-based dicarboxylic acid-functional monomers and polymers prepared from same THE SHERWIN-WILLIAMS COMPANY (US) 1996-04-23 US disclosed
US-5410078-A Styrene-based dicarboxylic acid-functional monomers and polymers prepared from same THE SHERWIN-WILLIAMS COMPANY (US) 1995-04-25 US disclosed
US-5405973-A Monomers for low temperature curable coatings THE SHERWIN-WILLIAMS COMPANY (US) 1995-04-11 US disclosed