SCHEMBL8847

SCHEMBL8847

C#CCCCC(=O)N1CCOCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.54
RAB9A P51151 5/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
POLB P06746 3/20 0.46
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
USP2 O75604 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
FKBP1A P62942 1/20 0.45
ALDH1A1 P00352 1/20 0.45
ATM Q13315 1/20 0.44
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
NPC1 O15118 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10937 0.95 GLA (0.53) GLARAB9AL3MBTL1POLBLMNA
SCHEMBL13779 0.89 L3MBTL1 (0.50) GLARAB9AL3MBTL1POLBLMNA
SCHEMBL11545 0.85 KDM4E (0.44) GLARAB9AL3MBTL1LMNAALDH1A1
SCHEMBL4811688 0.84 GLA (0.56) GLARAB9AL3MBTL1POLBLMNA
SCHEMBL31575913 0.83 ATM (0.65) RAB9AL3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL9415751 0.82 GLA (0.67) GLARAB9AL3MBTL1POLBLMNA
SCHEMBL10792 0.81 ATM (0.63) RAB9AL3MBTL1ALDH1A1ATMSMN1; SMN2
SCHEMBL7694058 0.81 GLA (0.65) GLARAB9AL3MBTL1POLBLMNA
SCHEMBL2704732 0.79 L3MBTL1 (0.55) GLARAB9AL3MBTL1POLBLMNA
SCHEMBL11908890 0.79 ATM (0.44) GLAL3MBTL1LMNAUSP2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980297-A Substituted aminopyridine compounds as EGFR inhibitors 柳韩洋行 2024-05-03 CN claimed
CN-120020131-A Aromatic ring benzothiazine derivative and medical application thereof 杭州百诚医药科技股份有限公司 2025-05-20 CN disclosed
CN-117980297-A Substituted aminopyridine compounds as EGFR inhibitors 柳韩洋行 2024-05-03 CN disclosed
US-20180118754-A1 COMPOUNDS RESPIVERT LTD. (GB) 2018-05-03 US disclosed
US-20180118754-A1 COMPOUNDS RESPIVERT LTD. (GB) 2018-05-03 US disclosed
US-20180118754-A1 COMPOUNDS RESPIVERT LTD. (GB) 2018-05-03 US disclosed
US-9834560-B2 Compounds RESPIVERT LTD. (GB) 2017-12-05 US disclosed
US-9834560-B2 Compounds RESPIVERT LTD. (GB) 2017-12-05 US disclosed
US-9834560-B2 Compounds RESPIVERT LTD. (GB) 2017-12-05 US disclosed
US-20160264583-A1 COMPOUNDS RESPIVERT LTD. (GB) 2016-09-15 US disclosed
US-8741909-B2 PI3 kinase inhibitors RESPIVERT LTD. (GB) 2014-06-03 US disclosed
US-8741909-B2 PI3 kinase inhibitors RESPIVERT LTD. (GB) 2014-06-03 US disclosed
US-8741909-B2 PI3 kinase inhibitors RESPIVERT LTD. (GB) 2014-06-03 US disclosed
EP-2491037-B1 QUINAZOLIN-4(3H)-ONE DERIVATIVES USED AS PI3 KINASE INHIBITORS RESPIVERT LTD (GB) 2014-04-30 EP disclosed
EP-2491037-A1 COMPOUNDS Respivert Limited (GB) 2012-08-29 EP disclosed
US-20120208799-A1 COMPOUNDS RESPIVERT LTD (GB) 2012-08-16 US disclosed
US-20120208799-A1 COMPOUNDS RESPIVERT LTD (GB) 2012-08-16 US disclosed
US-20120208799-A1 COMPOUNDS RESPIVERT LTD (GB) 2012-08-16 US disclosed
WO-2011048111-A1 COMPOUNDS RESPIVERT LIMITED (GB) 2011-04-28 WO disclosed
WO-2011048111-A1 COMPOUNDS RESPIVERT LIMITED (GB) 2011-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264583-A1 COMPOUNDS LTC4S, CYP11B2, LTB4R2 GLA 672/4885RAB9A 3822/4885L3MBTL1 4133/4885
US-20120208799-A1 COMPOUNDS LTC4S, CYP11B2, LTB4R2 GLA 672/4885RAB9A 3822/4885L3MBTL1 4133/4885
US-20180118754-A1 COMPOUNDS LTC4S, CYP11B2, LTB4R2 GLA 672/4885RAB9A 3822/4885L3MBTL1 4133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.