Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405936 | 0.76 | TSHR (0.38) | HSD17B10ALDH1A1CYP2C19CASP1CASP7 | |
| SCHEMBL5439062 | 0.75 | ALDH1A1 (0.46) | ALDH1A1CYP2C19TDP1CYP2C9 | |
| SCHEMBL251572 | 0.70 | CYP1A2 (0.37) | HSD17B10CYP2C19CYP1A2 | |
| SCHEMBL8847257 | 0.70 | KDM4E (0.47) | HSD17B10ALDH1A1CYP2C19TDP1CYP2C9 | |
| SCHEMBL8847163 | 0.69 | FABP3 (0.33) | FABP3FABP4FABP5 | |
| SCHEMBL27416843 | 0.67 | FABP3 (0.38) | HSD17B10ALDH1A1CASP1CASP7TDP1 | |
| SCHEMBL564054 | 0.67 | HSD17B10 (0.44) | HSD17B10ALDH1A1CASP1CASP7TDP1 | |
| SCHEMBL1224928 | 0.67 | PGAM1 (0.53) | HSD17B10ALDH1A1CASP1CASP7TDP1 | |
| SCHEMBL3395151 | 0.65 | BRD4 (0.52) | HSD17B10ALDH1A1TDP1CASP6 | |
| SCHEMBL5443614 | 0.65 | CA1 (0.43) | HSD17B10ALDH1A1CASP1TDP1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603557-B1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM CO (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5461126-A | Process of polymerizing olefins using organonickel catalyst compositions | PHILLIPS PETROLEUM COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5332708-A | Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0603557-A1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |