Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366220 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL29424116 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL6734016 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL3694892 | 0.80 | KMT2A (0.47) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL29456740 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL3694868 | 0.79 | KMT2A (0.46) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL3709925 | 0.79 | KMT2A (0.46) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL3702685 | 0.79 | KMT2A (0.46) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL27825821 | 0.78 | L3MBTL1 (0.48) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL4457662 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108712903-A | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy and amine 1, 4-benzoquinone derivatives for the treatment of oxidative stress disorders | 生物电子技术有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-103502218-B | Compounds and methods for for conjugating biomolecules | 生命科技公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20070197648-A1 | Pharmaceutical product containing tranilast | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |
| CN-1316977-C | Stable brivudine topical formulations | MENARINI RICERCHE SPA (IT) | 2007-05-23 | — | — | CN | disclosed |
| CN-1604782-A | Stabilized brivudine topical formulations | MENARINI RICERCHE SPA (IT) | 2005-04-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197648-A1 | Pharmaceutical product containing tranilast | PTGIS, TPMT, QDPR | ALDH1A1 141/4885KDM4E 1595/4885HPGD 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.