SCHEMBL8847155

SCHEMBL8847155

O=C(OCC1CO1)c1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.53
CYP1A2 P05177 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
MAPK1 P28482 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
HPGD P15428 1/20 0.48
MGLL Q99685 3/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21801767 0.89 DHFR (0.59) DHFRTSHRMAPK1L3MBTL1MGLL
SCHEMBL29374975 0.89 DHFR (0.59) DHFRTSHRMAPK1L3MBTL1MGLL
SCHEMBL121520 0.89 DHFR (0.59) DHFRTSHRMAPK1L3MBTL1MGLL
SCHEMBL28387457 0.84 DHFR (0.55) DHFRTSHRMAPK1L3MBTL1MGLL
SCHEMBL1537792 0.84 DHFR (0.55) DHFRMAPK1L3MBTL1MGLL
SCHEMBL15164276 0.83 TDP1 (0.56) DHFRTSHRMAPK1L3MBTL1MGLL
SCHEMBL21801769 0.83 DHFR (0.54) DHFRMAPK1L3MBTL1MGLL
SCHEMBL9770446 0.83 DHFR (0.54) DHFRTSHRMAPK1L3MBTL1MGLL
SCHEMBL30541879 0.83 DHFR (0.54) DHFRMAPK1L3MBTL1MGLL
SCHEMBL529997 0.83 DHFR (0.54) DHFRMAPK1L3MBTL1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP claimed
EP-0605937-A1 Antistatic resin composition DAISO CO., LTD. (JP) 1994-07-13 EP claimed
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP disclosed
US-5556916-A ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER WITH POLYOXYETHYLENE GLYCOL POLYMER OR COPOLYMER ON RUBBER SUBSTRATE DAISO CO. LTD. (JP) 1996-09-17 US disclosed
EP-0605937-A1 Antistatic resin composition DAISO CO., LTD. (JP) 1994-07-13 EP disclosed
US-4402974-A WITH CARBOXY, OXY, CARBO-AMINE AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1983-09-06 US disclosed