Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paranitrobenzyl Alcohol SCHEMBL5689999 | 0.84 | TSHR (0.56) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| SCHEMBL30643815 | 0.77 | CYP2C19 (0.64) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| SCHEMBL76204 | 0.77 | CYP2C19 (0.64) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| Malonic Acid SCHEMBL8982152 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTIDO1 | |
| SCHEMBL10999840 | 0.76 | MMP12 (0.58) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| SCHEMBL1369963 | 0.76 | CYP2C19 (0.62) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| Hydrochloric Acid SCHEMBL2527458 | 0.76 | CYP2C19 (0.62) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| SCHEMBL1369959 | 0.76 | CYP2C19 (0.62) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| SCHEMBL27861234 | 0.76 | CYP2C19 (0.62) | CYP2C19ALDH1A1TSHRCYP1A2LOXL2 | |
| SCHEMBL1554845 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700780-A | OLIGOPEPTIDE VIRICIDES; RIBONUCLEOTIDE REDUCTASE ENZYME INHIBITOR | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1997-12-23 | — | — | US | disclosed |
| EP-0493770-B1 | Antiherpes compositions | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-08-06 | — | — | EP | disclosed |
| EP-0493767-B1 | Synergistic combination for treating herpes infections | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1997-03-19 | — | — | EP | disclosed |
| US-5552384-A | Antiherpes compositions and method of use | BIO-MEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-09-03 | — | — | US | disclosed |
| EP-0411332-B1 | Antiviral peptides having a 2-oxoalkyl amino acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-12-06 | — | — | EP | disclosed |
| US-5380727-A | Antiviral nucleoside analog and a ribonucleotide reductase inhibiting peptide derivative | BIO-MEGA, INC. (CA) | 1995-01-10 | — | — | US | disclosed |
| EP-0326640-B1 | (1R,5S,6S)-2-SUBSTITUTED THIO-6 (R)-1-HYDROXYETHYL -1-METHYL-CARBAPENEM - CARBOXYLIC ACID DERIVATIVES | LEDERLE (JAPAN) LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| EP-0493770-A2 | Antiherpes compositions | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | disclosed |
| EP-0493767-A2 | Synergistic combination for treating herpes infections | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | disclosed |
| US-4990613-A | Bactericides | LEDERLE (JAPAN), LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0289801-B1 | (1R,5S,6S)-2-(substituted thio)-6-[(R)-1-hydroxy-ethyl]-1-methyl-carbapenem-3-carboxylic-acid derivatives | LEDERLE (JAPAN) LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4925836-A | NONTOXIC, SIDE EFFECT REDUCTION | LEDERLE (JAPAN), LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4925935-A | BACTERICIDES | LEDERLE (JAPAN), LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4866171-A | THIENAMYCIN ANTIBIOTIC | LEDERLE (JAPAN), LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0326640-A1 | (1R,5S,6S)-2-substituted thio-6 (R)-1-hydroxyethyl -1-methyl-carbapenem - carboxylic acid derivatives | LEDERLE (JAPAN) LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| EP-0289801-A1 | (1R,5S,6S)-2-(substituted thio)-6-[(R)-1-hydroxy-ethyl]-1-methyl-carbapenem-3-carboxylic-acid derivatives | LEDERLE (JAPAN) LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |