Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12034019 | 0.90 | OPRM1 (0.42) | DNM1OPRM1ALDH1A1TSHRLMNA | |
| SCHEMBL27997424 | 0.90 | OPRM1 (0.42) | DNM1OPRM1ALDH1A1TSHRLMNA | |
| SCHEMBL12034028 | 0.90 | OPRM1 (0.42) | DNM1OPRM1ALDH1A1TSHRLMNA | |
| Fluoride SCHEMBL29288452 | 0.79 | DNM1 (0.36) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL15868427 | 0.78 | DNM1 (0.39) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL27923968 | 0.76 | DNM1 (0.38) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL11769372 | 0.75 | OPRM1 (0.42) | DNM1OPRM1ALDH1A1TSHRLMNA | |
| SCHEMBL8138136 | 0.73 | — | — | |
| SCHEMBL12033982 | 0.72 | OPRM1 (0.44) | DNM1OPRM1ALDH1A1TSHRLMNA | |
| SCHEMBL12033980 | 0.72 | OPRM1 (0.44) | DNM1OPRM1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746572-A4 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 1997-03-26 | — | — | EP | claimed |
| EP-0746572-A1 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORPORATION (US) | 1996-12-11 | — | — | EP | claimed |
| WO-1995022566-A1 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORPORATION (US) | 1995-08-24 | — | — | WO | claimed |