Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847225 | 0.78 | DNM1 (0.36) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL6114912 | 0.74 | ALDH1A1 (0.39) | DNM1OPRM1ALDH1A1TDP1FDPS | |
| SCHEMBL6114908 | 0.74 | CA2 (0.41) | DNM1OPRM1ALDH1A1TSHRFDPS | |
| SCHEMBL9882797 | 0.74 | ALDH1A1 (0.39) | DNM1OPRM1ALDH1A1TDP1FDPS | |
| SCHEMBL729614 | 0.72 | DNM1 (0.32) | DNM1OPRM1 | |
| SCHEMBL28742933 | 0.72 | OPRM1 (0.46) | DNM1OPRM1TSHRFDPSLMNA | |
| Fluoride SCHEMBL29288452 | 0.72 | DNM1 (0.36) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL12034009 | 0.72 | OPRM1 (0.46) | DNM1OPRM1TSHRFDPSLMNA | |
| SCHEMBL3465318 | 0.70 | DNM1 (0.35) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL12034028 | 0.69 | OPRM1 (0.42) | DNM1OPRM1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309340-B2 | Ethylene-based polymer, polyethylene-based resin composition and use thereof, catalyst component for olefin polymerization, olefin polymerization catalyst containing the component, and method for producing ethylene-based polymer by using the catalyst | JAPAN POLYETHYLENE CORPORATION (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20140194277-A1 | ETHYLENE-BASED POLYMER, POLYETHYLENE-BASED RESIN COMPOSITION AND USE THEREOF, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, OLEFIN POLYMERIZATION CATALYST CONTAINING THE COMPONENT, AND METHOD FOR PRODUCING ETHYLENE-BASED POLYMER BY USING THE CATALYST | JAPAN POLYETHYLENE CORPORATION (JP) | 2014-07-10 | — | — | US | disclosed |