Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847286 | 0.75 | KMT2A (0.39) | HCAR2ALDH1A1ALOX15CYP1A2MEN1 | |
| SCHEMBL8847197 | 0.72 | ALDH1A1 (0.36) | ALDH1A1ALOX15CYP1A2MEN1KMT2A | |
| SCHEMBL836706 | 0.71 | LDHA (0.39) | HCAR2ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL836705 | 0.71 | LDHA (0.39) | HCAR2ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL3515862 | 0.69 | HCAR2 (0.37) | HCAR2ALDH1A1ALOX15CYP1A2MEN1 | |
| SCHEMBL3515866 | 0.69 | HCAR2 (0.37) | HCAR2ALDH1A1ALOX15CYP1A2MEN1 | |
| SCHEMBL8847241 | 0.69 | HSD17B10 (0.39) | HCAR2ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL8847156 | 0.68 | MEN1 (0.38) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL9812600 | 0.67 | CSNK2A1 (0.42) | HCAR2ALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL8847299 | 0.65 | HCAR2 (0.36) | HCAR2ALDH1A1ALOX15CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603557-B1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM CO (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5461126-A | Process of polymerizing olefins using organonickel catalyst compositions | PHILLIPS PETROLEUM COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5332708-A | Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0603557-A1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |