Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847348 | 1.00 | TRPV1 (0.46) | TRPV1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10308597 | 0.81 | TSHR (0.42) | TRPV1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL901259 | 0.81 | ALDH1A1 (0.41) | TRPV1ALDH1A1SMN1; SMN2MAPTBLM | |
| SCHEMBL5225784 | 0.81 | TSHR (0.42) | TRPV1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12835469 | 0.79 | TSHR (0.41) | TRPV1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16488743 | 0.78 | CTSK (0.47) | — | |
| SCHEMBL14673155 | 0.78 | CTSK (0.47) | — | |
| SCHEMBL16488750 | 0.78 | CTSK (0.47) | — | |
| SCHEMBL14673227 | 0.78 | CTSK (0.47) | — | |
| SCHEMBL25594806 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MAPTBLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552516-B1 | Aqueous synthetic organ-extracts | RIEMSCHNEIDER RANDOLPH DR DR P (DE) | 1997-09-10 | — | — | EP | disclosed |
| EP-0552516-A1 | Aqueous synthetic organ-extracts | SCHÀLKE & MAYR GMBH (DE) | 1993-07-28 | — | — | EP | disclosed |