Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241112 | 0.83 | PYGL (0.35) | ALDH1A1SMN1; SMN2PYGLCYP2C9SLC1A3 | |
| SCHEMBL901563 | 0.83 | PYGL (0.35) | ALDH1A1SMN1; SMN2PYGLCYP2C9SLC1A3 | |
| SCHEMBL903751 | 0.83 | PYGL (0.35) | ALDH1A1SMN1; SMN2PYGLCYP2C9SLC1A3 | |
| SCHEMBL6121051 | 0.83 | PYGL (0.35) | ALDH1A1SMN1; SMN2PYGLCYP2C9SLC1A3 | |
| SCHEMBL901561 | 0.83 | PYGL (0.35) | ALDH1A1SMN1; SMN2PYGLCYP2C9SLC1A3 | |
| SCHEMBL193140 | 0.83 | PYGL (0.35) | ALDH1A1SMN1; SMN2PYGLCYP2C9SLC1A3 | |
| SCHEMBL8847348 | 0.81 | TRPV1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL1534816 | 0.81 | PIN1 (0.34) | ALDH1A1TRPV1MEN1KMT2A | |
| SCHEMBL8847352 | 0.81 | TRPV1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL27258247 | 0.79 | ADAM17 (0.37) | ALDH1A1TRPV1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969620-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-03-03 | — | — | US | claimed |
| US-8969620-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-03-03 | — | — | US | disclosed |