SCHEMBL8847353

SCHEMBL8847353

NCc1ccc(Cl)c(CN)c1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PNMT P11086 4/20 0.50
▸ CSNK2A1 P68400 10/20 0.47
▸ TAAR1 Q96RJ0 2/20 0.45
▸ CSNK2A2 P19784 1/20 0.44
▸ CSNK2B P67870 1/20 0.44
▸ CSNK2A3 Q8NEV1 1/20 0.44
▸ LOX P28300 1/20 0.43
▸ LOXL3 P58215 1/20 0.43
▸ LOXL2 Q9Y4K0 1/20 0.43
▸ CYP2A6 P11509 1/20 0.41
▸ HRH3 Q9Y5N1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27881760 0.86 PNMT (0.46) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL27271778 0.85 CSNK2A1 (0.45) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL15047137 0.85 CSNK2A1 (0.43) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL27859143 0.85 CSNK2A1 (0.47) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL5847395 0.85 CSNK2A1 (0.57) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL2006591 0.81 CSNK2A1 (0.52) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL112200 0.80 PNMT (0.67) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL29349576 0.80 PNMT (0.67) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL16670732 0.80 CSNK2A1 (0.41) PNMTCSNK2A1TAAR1CSNK2A2CSNK2B
SCHEMBL19553649 0.80 PNMT (0.50) PNMTCSNK2A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636161-B1 MISCIBLE THERMOPLASTIC COMPOSITIONS CONTAINING POLYAMIDE/AMORPHOUS COPOLYAMIDE BLENDS ALLIED SIGNAL INC (US) 1997-07-30 — — EP disclosed
US-5391640-A A molding material blends consisting of a polyamide or a polylactam homopolymer and a polyamide copolymer which has aminoalkanoic acids, diamines and dicarboxylic acids monomer; vapor barriers; waterproofing, permselectivity ALLIEDSIGNAL INC. (US) 1995-02-21 — — US disclosed
EP-0636161-A1 MISCIBLE THERMOPLASTIC COMPOSITIONS CONTAINING POLYAMIDE/AMORPHOUS POLYAMIDE BLENDS. ALLIED SIGNAL INC (US) 1995-02-01 — — EP disclosed
WO-1993021276-A1 MISCIBLE THERMOPLASTIC COMPOSITIONS CONTAINING POLYAMIDE/AMORPHOUS POLYAMIDE BLENDS ALLIED-SIGNAL INC. (US) 1993-10-28 — — WO disclosed
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