Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847353 | 0.80 | PNMT (0.50) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL5847395 | 0.79 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL27271778 | 0.79 | CSNK2A1 (0.45) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL3467784 | 0.79 | CYP3A4 (0.48) | PNMTTAAR1 | |
| SCHEMBL31477448 | 0.77 | CA2 (0.53) | — | |
| SCHEMBL3507727 | 0.76 | TDP1 (0.43) | — | |
| SCHEMBL15047137 | 0.75 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL27859143 | 0.75 | CSNK2A1 (0.47) | CSNK2A1CSNK2A2CSNK2BCSNK2A3PNMT | |
| SCHEMBL23891902 | 0.74 | AOC1 (0.34) | CSNK2A1CSNK2A2CSNK2BCSNK2A3LOXL2 | |
| SCHEMBL3454581 | 0.73 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015059618-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-30 | — | — | WO | disclosed |