Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.43 |
| ▸ | PNMT | P11086 | 3/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847353 | 0.85 | PNMT (0.50) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL27271778 | 0.83 | CSNK2A1 (0.45) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL15047147 | 0.83 | CSNK2A1 (0.47) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL15047124 | 0.80 | HRH3 (0.40) | CSNK2A1PNMTTAAR1LOXLOXL3 | |
| SCHEMBL14601105 | 0.79 | TRPA1 (0.39) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL27859143 | 0.79 | CSNK2A1 (0.47) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL5847395 | 0.79 | CSNK2A1 (0.57) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL112200 | 0.75 | PNMT (0.67) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL29349576 | 0.75 | PNMT (0.67) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL16670732 | 0.75 | CSNK2A1 (0.41) | CSNK2A1PNMTCSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066623-B1 | PROCESS FOR PRODUCING 1-(3,4-DICHLOROBENZYL)-5-OCTYLBIGUANIDE OR A SALT THEREOF | OTSUKA PHARMA CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |