Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847140 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2TBXAS1TDP1CHRM1 | |
| SCHEMBL8847136 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2TBXAS1TDP1CHRM1 | |
| SCHEMBL7557794 | 0.75 | CHRM1 (0.62) | GRIK1GRIK2TBXAS1TSHRTDP1 | |
| SCHEMBL5053789 | 0.75 | CHRM1 (0.62) | GRIK1GRIK2TBXAS1TSHRTDP1 | |
| SCHEMBL379205 | 0.73 | GRIK1 (0.64) | GRIK1GRIK2TBXAS1TDP1CHRM1 | |
| SCHEMBL8847127 | 0.73 | GRIK1 (0.50) | GRIK1GRIK2TBXAS1TDP1CHRM1 | |
| SCHEMBL7551496 | 0.72 | CA2 (0.61) | GRIK1GRIK2TBXAS1TDP1CHRM1 | |
| SCHEMBL8847129 | 0.71 | GRIK1 (0.44) | GRIK1GRIK2TBXAS1FNTAFNTB | |
| SCHEMBL28435149 | 0.71 | FOLH1 (0.56) | GRIK1GRIK2 | |
| SCHEMBL8847368 | 0.70 | GRIK1 (0.47) | GRIK1GRIK2TBXAS1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778820-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1997-06-18 | — | — | EP | claimed |
| WO-1996006821-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1996-03-07 | — | — | WO | claimed |