SCHEMBL8848044

SCHEMBL8848044

CCCCCCCCCCCCOCC(O)COc1cc(O)c(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)cc1CCCCCC

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 11/20 0.37
PLA2G4B P0C869 1/20 0.34
USP2 O75604 1/20 0.34
HTT P42858 1/20 0.33
VDR P11473 1/20 0.33
CNR1 P21554 5/20 0.33
LPAR5 Q9H1C0 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
NFKB1 P19838 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LTB4R Q15722 1/20 0.32
LTB4R2 Q9NPC1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848384 0.98 CNR2 (0.35) CNR2PLA2G4BUSP2HTTVDR
SCHEMBL8848129 0.88 ESR1 (0.39) CNR2HTTCNR1NR1H4NPC1
SCHEMBL8848347 0.88 PLA2G4B (0.38) CNR2PLA2G4BTP53SMN1; SMN2
SCHEMBL8855632 0.88 MAPT (0.36) CNR2PLA2G4BUSP2HTTMAPK1
SCHEMBL29008146 0.87 CNR1 (0.37) CNR2PLA2G4BUSP2HTTVDR
SCHEMBL8848709 0.85 CNR2 (0.38) CNR2PLA2G4BUSP2HTTSMN1; SMN2
SCHEMBL4625753 0.84 PLA2G4B (0.44) CNR2PLA2G4BUSP2HTTLPAR5
SCHEMBL18231906 0.84 PLA2G4B (0.44) CNR2PLA2G4BUSP2HTTLPAR5
SCHEMBL31370 0.84 PLA2G4B (0.44) CNR2PLA2G4BUSP2HTTLPAR5
SCHEMBL7524555 0.84 PLA2G4B (0.44) CNR2PLA2G4BUSP2HTTLPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
US-5648488-A Compositions stabilized with red-shifted tris-aryl-s-triazines CIBA-GEIGY CORPORATION (US) 1997-07-15 US disclosed
US-5637706-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5556973-A Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1996-09-17 US disclosed
US-5543518-A ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES CIBA-GEIGY CORPORATION (US) 1996-08-06 US disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed