SCHEMBL8848129

SCHEMBL8848129

CCCCCCOc1cc(O)c(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)cc1CCCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.39
NR1H4 Q96RI1 2/20 0.39
MAPK1 P28482 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
RAD52 P43351 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LTB4R Q15722 3/20 0.39
LTB4R2 Q9NPC1 3/20 0.39
CNR1 P21554 7/20 0.39
CNR2 P34972 7/20 0.39
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011638 0.95 NR1H4 (0.37) ESR1NR1H4MAPK1MEN1MAPT
SCHEMBL8848044 0.88 CNR2 (0.37) NR1H4MAPK1HTTLTB4RLTB4R2
SCHEMBL8848507 0.88 LTB4R (0.45) NR1H4MAPK1MEN1MAPTHTT
SCHEMBL8848384 0.86 CNR2 (0.35) MAPK1MEN1HTTKMT2ACNR1
SCHEMBL8848576 0.86 MAPT (0.44) ESR1MAPK1MEN1MAPTHTT
SCHEMBL8848347 0.84 PLA2G4B (0.38) CNR2TP53SMN1; SMN2
SCHEMBL8855598 0.83 LTB4R (0.43) NR1H4MAPK1MEN1MAPTHTT
SCHEMBL8848364 0.82 LTB4R (0.44) ESR1NR1H4MEN1MAPTHTT
SCHEMBL8848177 0.82 LTB4R (0.44) ESR1NR1H4MEN1MAPTHTT
SCHEMBL665375 0.81 NR5A1 (0.41) ESR1MEN1MAPTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed
US-5648488-A Compositions stabilized with red-shifted tris-aryl-s-triazines CIBA-GEIGY CORPORATION (US) 1997-07-15 US disclosed
US-5637706-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5556973-A Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1996-09-17 US disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed