SCHEMBL8848709

SCHEMBL8848709

CCCCCCCCCOCC(O)COc1cc(O)c(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1CCCCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.38
PLA2G4B P0C869 1/20 0.38
LTB4R Q15722 5/20 0.36
LTB4R2 Q9NPC1 5/20 0.36
USP2 O75604 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR1 P03372 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SOAT1 P35610 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848324 0.98 PLA2G4B (0.38) CNR2PLA2G4BLTB4RLTB4R2USP2
SCHEMBL8848297 0.98 PLA2G4B (0.38) CNR2PLA2G4BLTB4RLTB4R2USP2
SCHEMBL8855573 0.92 PLA2G4B (0.36) CNR2PLA2G4BLTB4RLTB4R2USP2
SCHEMBL8855632 0.90 MAPT (0.36) CNR2PLA2G4BLTB4RLTB4R2USP2
SCHEMBL8848177 0.88 LTB4R (0.44) CNR2LTB4RLTB4R2USP2KDM4E
SCHEMBL8848364 0.88 LTB4R (0.44) CNR2LTB4RLTB4R2USP2KDM4E
SCHEMBL8848044 0.85 CNR2 (0.37) CNR2PLA2G4BLTB4RLTB4R2USP2
SCHEMBL8848384 0.83 CNR2 (0.35) CNR2PLA2G4BUSP2KDM4EMEN1
SCHEMBL6562548 0.82 PLA2G4B (0.47) CNR2PLA2G4BUSP2KDM4EALDH1A1
SCHEMBL6341883 0.81 PLA2G4B (0.46) CNR2PLA2G4BGAAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed
US-5648488-A Compositions stabilized with red-shifted tris-aryl-s-triazines CIBA-GEIGY CORPORATION (US) 1997-07-15 US disclosed
US-5637706-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5556973-A Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1996-09-17 US disclosed
US-5543518-A ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES CIBA-GEIGY CORPORATION (US) 1996-08-06 US disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed