Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848027 | 0.78 | ELANE (0.48) | — | |
| SCHEMBL7874058 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL13038658 | 0.70 | PPARA (0.37) | PPARA | |
| SCHEMBL8848023 | 0.65 | APP (0.44) | — | |
| SCHEMBL4202571 | 0.61 | KIF11 (0.45) | — | |
| SCHEMBL10867877 | 0.61 | PTPN1 (0.45) | PPARA | |
| SCHEMBL6508516 | 0.61 | PPARA (0.37) | PPARA | |
| SCHEMBL3872299 | 0.61 | ALDH1A1 (0.64) | PPARA | |
| SCHEMBL3271614 | 0.60 | HIF1A (0.52) | PPARA | |
| SCHEMBL8494644 | 0.60 | SLC13A5 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663416-A | ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS OR DERMATITIS TREATMENT | CORTECH INC. | 1997-09-02 | — | — | US | claimed |
| US-5663416-A | ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS OR DERMATITIS TREATMENT | CORTECH INC. | 1997-09-02 | — | — | US | disclosed |