SCHEMBL8848637

SCHEMBL8848637

Cc1cc(C)c(CC(=O)CC2(C)CCC(C(C)C)CC2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9069099 0.84 THRB (0.34) EPHX2P2RX7
SCHEMBL8090997 0.82 P2RX3 (0.32)
Bicarbonate SCHEMBL9069859 0.81 FFAR4 (0.34) P2RX7
Bicarbonate SCHEMBL8848378 0.80 DPP4 (0.33)
Bicarbonate SCHEMBL8848396 0.79 CHRM2 (0.34) P2RX7
SCHEMBL8906535 0.73 PYGL (0.34) EPHX2P2RX7
SCHEMBL8906549 0.72 MAPT (0.32) P2RX7
SCHEMBL28777690 0.70 CYP1A2 (0.37)
SCHEMBL8796943 0.69 LPAR1 (0.38)
Bicarbonate SCHEMBL7617866 0.69 KMT2A (0.41) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0769001-A1 2-ARYL CYCLOPENTANE-1,3-DIONE DERIVATIVES BAYER AG (DE) 1997-04-23 EP disclosed
WO-1996001798-A1 2-ARYL CYCLOPENTANE-1,3-DIONE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1996-01-25 WO disclosed