SCHEMBL8848639

SCHEMBL8848639

CCCCCCc1c[c]c(O)cc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.54
TYR P14679 3/20 0.54
MEN1 O00255 2/20 0.54
CYP3A4 P08684 2/20 0.54
MAPT P10636 2/20 0.54
HTT P42858 2/20 0.54
KMT2A Q03164 2/20 0.54
TP53 P04637 1/20 0.54
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
PTGS2 P35354 6/20 0.43
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
EP300 Q09472 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4656377 0.93 TYR (0.52) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL11060195 0.86 ALOX5 (0.50) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL28932575 0.85 HMGCR (0.46) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL9250407 0.83 ALOX5 (0.44) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL27451394 0.81 ALOX5 (0.42) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL27805061 0.81 ALOX5 (0.45) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL10671033 0.80 ALOX5 (0.49) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL2344847 0.78 ALOX5 (0.68) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL8589296 0.78 ALOX5 (0.68) ALOX5TYRMEN1CYP3A4MAPT
SCHEMBL2348704 0.78 ALOX5 (0.68) ALOX5TYRMEN1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed
US-5648488-A Compositions stabilized with red-shifted tris-aryl-s-triazines CIBA-GEIGY CORPORATION (US) 1997-07-15 US disclosed
US-5637706-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5556973-A Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1996-09-17 US disclosed
US-5543518-A ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES CIBA-GEIGY CORPORATION (US) 1996-08-06 US disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed