SCHEMBL8855573

SCHEMBL8855573

CCCCCCc1cc(-c2ncnc(-c3ccccc3)n2)c(O)cc1OCC(O)COCCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 1/20 0.36
CNR2 P34972 4/20 0.35
LTB4R Q15722 3/20 0.35
LTB4R2 Q9NPC1 3/20 0.35
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
APAF1 O14727 1/20 0.34
USP2 O75604 1/20 0.34
ESR1 P03372 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848297 0.94 PLA2G4B (0.38) PLA2G4BCNR2LTB4RLTB4R2KDM4E
SCHEMBL8848324 0.94 PLA2G4B (0.38) PLA2G4BCNR2LTB4RLTB4R2KDM4E
SCHEMBL8848709 0.92 CNR2 (0.38) PLA2G4BCNR2LTB4RLTB4R2KDM4E
SCHEMBL8855632 0.85 MAPT (0.36) PLA2G4BCNR2LTB4RLTB4R2KDM4E
SCHEMBL27769450 0.81 MAPT (0.47) KDM4ESMN1; SMN2ALDH1A1MEN1APAF1
SCHEMBL8848384 0.81 CNR2 (0.35) PLA2G4BCNR2KDM4ESMN1; SMN2ALDH1A1
SCHEMBL8848364 0.80 LTB4R (0.44) CNR2LTB4RLTB4R2KDM4ESMN1; SMN2
SCHEMBL8848177 0.80 LTB4R (0.44) CNR2LTB4RLTB4R2KDM4ESMN1; SMN2
SCHEMBL8848044 0.79 CNR2 (0.37) PLA2G4BCNR2LTB4RLTB4R2SMN1; SMN2
SCHEMBL8855598 0.78 LTB4R (0.43) CNR2LTB4RLTB4R2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed