Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848912 | 0.90 | LTA4H (0.54) | NPC1RAB9AL3MBTL1LTA4HTP53 | |
| SCHEMBL8848722 | 0.88 | RAB9A (0.65) | MAOBNPC1RAB9AL3MBTL1LTA4H | |
| SCHEMBL8848575 | 0.84 | MAOB (0.54) | MAOBNPC1RAB9ALTA4H | |
| SCHEMBL8848799 | 0.84 | LTA4H (0.50) | MAOBNPC1RAB9AL3MBTL1LTA4H | |
| SCHEMBL8848642 | 0.84 | HSD17B10 (0.52) | NPC1RAB9AL3MBTL1LTA4HTP53 | |
| SCHEMBL8848714 | 0.83 | HSD17B10 (0.51) | NPC1RAB9AL3MBTL1LTA4HTP53 | |
| Hydrochloric Acid SCHEMBL8848858 | 0.82 | LTA4H (0.62) | NPC1RAB9ALTA4HELANECYP2C9 | |
| SCHEMBL8848788 | 0.82 | MEN1 (0.64) | NPC1RAB9AL3MBTL1LTA4HTP53 | |
| SCHEMBL8848534 | 0.82 | LTA4H (0.60) | NPC1RAB9AL3MBTL1LTA4HTP53 | |
| SCHEMBL8848588 | 0.81 | LTA4H (0.48) | MAOBNPC1RAB9AL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |