Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12776819 | 0.78 | GPR35 (0.56) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8848416 | 0.73 | TTR (0.58) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8848721 | 0.72 | TTR (0.56) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8848361 | 0.72 | TTR (0.56) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8848629 | 0.71 | XDH (0.45) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8848633 | 0.70 | TTR (0.44) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL30593957 | 0.70 | ALOX15 (0.55) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL26110717 | 0.70 | ALOX15 (0.55) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL30593958 | 0.70 | ALOX15 (0.55) | GPR35MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL27691689 | 0.70 | HPGD (0.51) | GPR35MEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444899-B1 | Catechol derivatives, their physiologically acceptable salts, esters and their use in the treatment of tissue damage induced by lipid peroxidation | ORION YHTYMAE OY (FI) | 1997-02-05 | — | — | EP | claimed |