Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554756 | 0.85 | ACHE (0.48) | PIN1CYP3A4MAPT | |
| SCHEMBL29227277 | 0.85 | ACHE (0.48) | PIN1CYP3A4MAPT | |
| SCHEMBL8848542 | 0.83 | ELANE (0.51) | ELANECA2 | |
| SCHEMBL27389222 | 0.82 | MEN1 (0.53) | PIN1GRK6MAPTSMN1; SMN2 | |
| SCHEMBL12896130 | 0.79 | GABRA1 (0.48) | MAPT | |
| SCHEMBL8848754 | 0.78 | GRK6 (0.37) | ELANEGRK6CYP3A4MAPTCA2 | |
| SCHEMBL703677 | 0.77 | DCUN1D1 (0.54) | PIN1GRK6MAPT | |
| SCHEMBL8848806 | 0.77 | KDM4E (0.42) | ELANEGRK6CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL13542931 | 0.77 | ACHE (0.38) | GRK6SMN1; SMN2 | |
| SCHEMBL4642463 | 0.76 | CYP1A2 (0.49) | PIN1GRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |