Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | TGM2 | P21980 | 2/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387978 | 0.91 | FOLH1 (0.65) | SIRT2SIRT1CTSLCTSSFOLH1 | |
| SCHEMBL8953569 | 0.90 | SIRT2 (0.59) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL8953566 | 0.90 | SIRT2 (0.59) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL17694104 | 0.90 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSFOLH1 | |
| SCHEMBL11308449 | 0.90 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSFOLH1 | |
| SCHEMBL17279329 | 0.90 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSFOLH1 | |
| Hydrochloric Acid SCHEMBL10586697 | 0.89 | SIRT2 (0.58) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL10908895 | 0.89 | PRSS1 (0.57) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL10908888 | 0.89 | PRSS1 (0.57) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL31243057 | 0.89 | CTSL (0.57) | SIRT2SIRT1CTSLCTSSFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5695737-A | CONTRAST MEDIA FOR NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |