Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848990 | 0.84 | KDM4E (0.31) | AR | |
| SCHEMBL7569248 | 0.84 | PTGS2 (0.48) | LTB4RLTB4R2ALOX5PTGS2PPARA | |
| SCHEMBL17060529 | 0.84 | AR (0.46) | LTB4RLTB4R2ARSLC6A2SLC6A4 | |
| SCHEMBL27816131 | 0.83 | AR (0.37) | LTB4RLTB4R2ARALOX5PTGS2 | |
| SCHEMBL28541193 | 0.81 | LTB4R (0.44) | LTB4RLTB4R2ARALOX5PTGS2 | |
| SCHEMBL8763456 | 0.77 | GABRA1 (0.36) | ARSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18784878 | 0.77 | LTB4R (0.42) | LTB4RLTB4R2ALOX5PTGS2SLC6A2 | |
| SCHEMBL29263979 | 0.77 | LTB4R (0.42) | LTB4RLTB4R2ALOX5PTGS2SLC6A2 | |
| SCHEMBL10880963 | 0.77 | LTB4R (0.42) | LTB4RLTB4R2ALOX5PTGS2SLC6A2 | |
| SCHEMBL11615164 | 0.75 | LTB4R (0.41) | LTB4RLTB4R2ALOX5PTGS2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5623006-A | HAVING GAP FILLED WITH CURED POLYCYANURATE BINDER | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |
| US-5536765-A | CYANATE TRIMERIZATION | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |
| US-5468790-A | Useful in forming interconnection structures for integrated semiconductor devices | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0604823-A1 | Triazine polymer and use thereof | International Business Machines Corporation (US) | 1994-07-06 | — | — | EP | disclosed |