Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992711 | 0.83 | RARG (0.45) | RARGRXRA | |
| SCHEMBL20399340 | 0.76 | RARG (0.44) | RARGRXRA | |
| SCHEMBL8356805 | 0.71 | RARG (0.41) | RARGRXRA | |
| SCHEMBL8853218 | 0.70 | RXRA (0.46) | RARGRXRA | |
| SCHEMBL9216823 | 0.68 | RARG (0.47) | RARGRXRA | |
| SCHEMBL9211089 | 0.68 | RARG (0.47) | RARGRXRA | |
| SCHEMBL8853596 | 0.68 | RXRA (0.43) | RARGRXRA | |
| SCHEMBL8749985 | 0.68 | RARG (0.42) | RARGRXRA | |
| SCHEMBL20816041 | 0.67 | ALOX5 (0.48) | — | |
| SCHEMBL23633279 | 0.67 | RARG (0.52) | RARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561447-B1 | Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT | QUEST INT (NL) | 1997-01-02 | — | — | EP | claimed |
| US-5430015-A | Acylation of tetralins | UNILEVER PATENT HOLDINGS, BV (NL) | 1995-07-04 | — | — | US | claimed |
| EP-0561447-A1 | Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT | QUEST INTERNATIONAL B.V. (NL) | 1993-09-22 | — | — | EP | claimed |
| EP-0561447-B1 | Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT | QUEST INT (NL) | 1997-01-02 | — | — | EP | disclosed |
| US-5430015-A | Acylation of tetralins | UNILEVER PATENT HOLDINGS, BV (NL) | 1995-07-04 | — | — | US | disclosed |
| EP-0561447-A1 | Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT | QUEST INTERNATIONAL B.V. (NL) | 1993-09-22 | — | — | EP | disclosed |