Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849584 | 1.00 | LTB4R (0.44) | LTB4RMAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8850299 | 0.89 | LTB4R (0.45) | LTB4RMAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8850303 | 0.89 | LTB4R (0.45) | LTB4RMAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8849767 | 0.88 | LTB4R (0.44) | LTB4RMAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8849756 | 0.88 | LTB4R (0.44) | LTB4RMAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8850289 | 0.83 | LTB4R (0.64) | LTB4RTP53CYP3A4NFKB1MEN1 | |
| SCHEMBL8849559 | 0.83 | LTB4R (0.43) | LTB4RMAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8870066 | 0.83 | LTB4R (0.64) | LTB4RTP53CYP3A4NFKB1MEN1 | |
| SCHEMBL8849878 | 0.83 | LTB4R (0.64) | LTB4RTP53CYP3A4NFKB1MEN1 | |
| SCHEMBL8849921 | 0.83 | LTB4R (0.64) | LTB4RTP53CYP3A4NFKB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650953-B1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-06-04 | — | — | EP | disclosed |
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |
| EP-0650953-A1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-05-03 | — | — | EP | disclosed |