Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850303 | 1.00 | LTB4R (0.45) | LTB4RALDH1A1MAPK1MTORPMP22 | |
| SCHEMBL8849767 | 0.89 | LTB4R (0.44) | LTB4RALDH1A1MAPK1MTORPMP22 | |
| SCHEMBL8849572 | 0.89 | LTB4R (0.44) | LTB4RALDH1A1MAPK1MTORPMP22 | |
| SCHEMBL8849756 | 0.89 | LTB4R (0.44) | LTB4RALDH1A1MAPK1MTORPMP22 | |
| SCHEMBL8849584 | 0.89 | LTB4R (0.44) | LTB4RALDH1A1MAPK1MTORPMP22 | |
| SCHEMBL8849559 | 0.84 | LTB4R (0.43) | LTB4RALDH1A1MAPK1MTORPMP22 | |
| SCHEMBL8849832 | 0.84 | LTB4R (0.64) | LTB4RALDH1A1CYP3A4NFKB1ALOX15 | |
| SCHEMBL8849878 | 0.84 | LTB4R (0.64) | LTB4RALDH1A1CYP3A4NFKB1ALOX15 | |
| SCHEMBL8870066 | 0.84 | LTB4R (0.64) | LTB4RALDH1A1CYP3A4NFKB1ALOX15 | |
| SCHEMBL8849575 | 0.84 | LTB4R (0.43) | LTB4RALDH1A1MAPK1MTORPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650953-B1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-06-04 | — | — | EP | disclosed |
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |
| EP-0650953-A1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-05-03 | — | — | EP | disclosed |